| DAO | Windows Registry Backup |
| DAP | Data access page (Microsoft Access 2000) |
| DAT | Data file |
| DAT | A data file extension used to designate an error message in a inbound internet email message (Microsoft Exchange Server v 5.0) |
| DAT | WordPerfect Merge Data |
| DAT | Extension used for some MPEG files |
| DB | Borderland's Paradox 7 table database |
| DBC | Microsoft's Visual FoxPro database container file |
| DBF | A dBASE file, a format originated by Ashton-Tate, but understood by Act!, Clipper,FoxPro, Arago, Wordtech, xBase, and similar database or database-related products. |
| DBF | Enable database (can be opened with Excel 97) |
| DBF | Oracle 8.1.x tablespace file |
| DBK | dBase Database Backup |
| DBK | Schematic backup file (Orcad Schematic Capture) |
| DBO | Compiled program file (dBase IV) |
| DBQ | Paradox Memo |
| DBT | dBase Text Memo |
| DBV | Memo field file (Flexfile 2) |
| DBW | Microsoft Windows 9.x Database file (DataBoss) |
| DBX | DataBeam image |
| DBX | Microsoft's Visual Foxpro Table file |
| DC | CAD file (DesignCAD) |
| DC2 | CAD file (DesignCAD) |
| DCA | Document Content Architecture Text file (IBM DisplayWrite) |
| DCA | Visual Basic Active designer cache |
| DCD | Document content description file (used in XML) |
| DCF | Disk Image file |
| DCF | Data file (Dyadic) |
| DCIM | Digital Imaging and Communications in Medicine (image and data) |
| DCM | DCM module |
| DCP | Data CodePage (OS/2) |
| DCR | Shockwave file |
| DCS | Desktop Color Separation file |
| DCS | Bitmap Graphics (Quark XPress) |
| DCS | Datafile (ACT! Activity file) |
| DCT | Microsoft's Visual FoxPro database container file |
| DCT | Database Dictionary file (Clarion Database Developer) |
| DCT | Database SpellCheck Dictionary (Harvard Graphics 3.0-Symphony) |
| DCU | Delphi compiled unit |
| DCX | Microsoft's Visual FoxPro database container file |
| DCX | Fax image (based on PCX) |
| DCX | Macro file |
| DCX | Bitmap Graphics file (Multipage PCX) |
| DC5 | DataCAD Drawing |
| DD | Compressed Archive (Macintosh DISKDOUBLER) |
| DDB | Bitmap Graphics file |
| DDF | Btrieve or Xtrieve Data Definition File, which contains metadata describing a Btrieve or Xtrieve file |
| DDI | Image File (DISKDUPE) |
| DDIF | Digital Equipment or Compaq file. Used for storing images and their word processing documents |
| DDP | Device Driver Profile (OS/2) |
| DEB | Debug Script (DOS Debug) |
| DEF | SmartWare II data |
| DEF | Define Module file (3-D Fassade Plus) |
| DEF | C++ definition file |
| DEF | Assembly Header file (Geoworks) |
| DEFI | Oracle 7 de-install script |
| DEI | Design Engineered Interface (GSI), Gerber Systems Inc.) |
| DEM | Demo file (Descent) |
| DEM | A file with USGS standards for Digital Elevation Models (Vista Pro) |
| DEM | Graphics file (Vista Pro) |
| DEP | Visual Basic Setup Wizard Dependency file |
| DER | Certificate file |
| DEV | Device Driver |
| DEWF | Macintosh SoundCap/SoundEdit recorded instrument file |
| DEZ | Encrypted zip file (DES Encryption) |
| DFD | Data Flow Diagram Graphic (Prosa) |
| DFI | Outline Font description (Digifont) |
| DFL | Default Program Settings (Signature) |
| DFM | Data Flow Diagram model (Prosa) |
| DFS | Sound File (Delight) |
| DFV | Printing Form value (Microsoft Word) |
| DGN | Microstation95 CAD drawing |
| DGS | Diagnostics Report |
| DH | Dependency Information file (Geoworks) |
| DHP | Graphic file (Dr. Halo II-III PIC Format) |
| DHT | Datafile (Gauss) |
| DIA | Diagraph Graphics file (Computer Support Corporation) |
| DIB | Device-independent bitmap |
| DIC | Dictionary file |
| DIC | Dictionary file (Lotus Notes, Domino) |
| DICM | Digital imaging and communications in medicine file (DICOM) |
| DIF | Data Interchange Format spreadsheet |
| DIF | Database file (VisiCalc) |
| DIF | Data Interchange Output file |
| DIF | Text file (Output from Data Interchange Format) |
| DIG | Digilink file |
| DIG | Sound Designer I audio |
| DIP | Graphics file |
| DIR | Macromedia Director file |
| DIR | Dialing Directory (ProComm Plus) |
| DIR | Directory (VAX) (DEC) |
| DIR | Movie (MacroMind Director 4.x) |
| DIS | Ray Tracer file |
| DIS | Distribution file (VAX Mail) |
| DIS | Thesaurus file (CorelDraw) |
| DIT | Active directory schema (Microsoft Windows 2000) |
| DIZ | Description file (Description in ZIP) |
| DKB | Graphics file (Ray Traced DKBTrace) |
| DL | Image |
| DLD | Datafile (Lotus 1-2-3) |
| DLG | C++ Dialogue Script |
| DLL | Dynamic-link library file |
| DLL | Export/Import Filter (CorelDraw) |
| DLS | Downloadable sound |
| DLS | Interactive music architecture (IMA)(Microsoft),(Blood2) |
| DLS | Setup file (Norton DiskLock) |
| DMD | Visual dBASE data module |
| DMF | Packed Amiga disk image |
| DMF | X-Trakker music module (MOD) |
| DMO | Demo file (Derive) |
| DMP | Dump file (Screen or Memory) |
| DMS | Compressed Archive (Amiga DISKMASHER) |
| DOB | Visual Basic User document |
| DOC | FrameMaker or FrameBuilder document |
| DOC | WordStar document |
| DOC | WordPerfect document |
| DOC | Microsoft Word document |
| DOC | DisplayWrite document |
| DOC | Document format (Interleaf) |
| DOG | Screen Saver file (Laughing Dog Screen Saver) |
| DOH | Dependency Information file (Geoworks) |
| DOS | External Command file (1st Reader) |
| DOS | Network Driver file (PKT_DIS.dos) |
| DOS | Text file (DOS) |
| DOT | Word Document Template (Microsoft Word for Windows) |
| DOT | Line-Type definition (CorelDraw) |
| DOX | User document binary form (Visual Basic) |
| DOX | Text file (MultiMate 4.x) |
| DOZ | Description out of Zip (VENDINFO) |
| DP | Calendar file (Daily Planner) |
| DP | Datafile (DataPhile) |
| DPJ | DeskProto project file (DeskProto CAM) |
| DPL | Borland Delphi 3 packed library |
| DPR | Project header (Borland C++) |
| DPT | Publication file (Publish-It!) |
| DRAW | Acorn's object-based vector image |
| DRC | Design rules check report file (Orcad Schematic Capture) |
| DRS | Display Resource file (Microsoft WordPerfect for Windows) |
| DRV | Driver |
| DRV | Device Driver (Required to make a device function) |
| DRW | Vector graphics (Micrografx) |
| DRW | Lotus Freelance Image |
| DRW | Pro/E drawing |
| DS4 | Micrografx Designer Image |
| DR9 | Directory file |
| DS4 | Vector Graphics (Micrografx) |
| DSC | Discard file (Oracle) |
| DSD | Database file (DataShaper) |
| DSD | Document structure definition file (Used in XML) |
| DSF | Micrografx Designer v7.x file |
| DSG | DooM saved game |
| DSK | Project Desktop file (Borland C++/Turbo Pascal) |
| DSK | Driver file (Novell Netware) |
| DSM | Dynamic Studio music module (MOD) |
| DSM | Digital Sound Module (DSI) |
| DSM | Music module file (DSIK) |
| DSN | ODBC Data source |
| DSN | Design (Object System Designer) |
| DSN | Schematic file (Orcad Schematic Capture) |
| DSP | Microsoft Developer Studio project |
| DSP | Display parameters (Signature) |
| DSP | Graphics Display driver (Dr. Halo) |
| DSQ | Corel QUERY |
| DSR | Visual Basic Active designer file |
| DSR | Driver Resource (Microsoft WordPerfect for Windows) |
| DSS | Screensaver file (DCC) |
| DSS | Digital Sound file (Digital Soup)) |
| DST | Embroidery machines graphic file |
| DST | Distribution file (PC-RDist, by Pyzzo) |
| DSW | Desktop settings (Borland C++ 4.5) |
| DSW | Microsoft Developer Studio workspace file |
| DSX | Visual Basic Active designer binary file |
| DT_ | Data file fork (Macintosh) |
| DTA | World Bank's STARS data |
| DTA | Datafile (Turbo C++) |
| DTD | SGML Document Type Definition (DTD) file |
| DTED | Digital terrain elevation data (geographic data format) |
| DTF | Database file (PFS-Questions & Answers) |
| DTF | Symantec Q&A relational database |
| DTM | Module file (DigiTrakker) |
| DTP | Desktop layout file (SecurDesk!/SecurDesk! LV) |
| DTP | Text Document (Timeworks Publisher 3.x) |
| DTP | Template file (Pressworks) |
| DUN | Microsoft Dial-up Networking Export file |
| DUP | Duplicate Backup |
| DV | Digital video (MIME) |
| DVC | Datafile (Lotus 1-2-3) |
| DVF | Graphics file associated with camcorders (DV Studio) |
| DVI | Binary file (TeX) |
| DVI | Device Independent Document (TeX) (LaTeX) |
| DVP | Desqview Program information (DESQview) |
| DVP | Device parameter file (AutoCAD) |
| DW2 | Drawing file (DesignCAD for Windows) |
| DWC | Compressed Archive (DWC) |
| DWD | DiamondWare digitized file |
| DWF | Vector graphic (Autodesk) |
| DWF | CAD drawing in Vector Graphics format |
| DWF | Drawing Web file (Microsoft WHIP autoCAD reader) |
| DWG | AutoCAD Drawing |
| DWG | AutoCAD drawing, or older Generic CAD drawing file |
| DWP | Document file (DeScribe) |
| DWS | Workspace file (Dyadic) |
| DWT | Template file, or prototype (AutoCAD) |
| DX | Digital Electric Corporation (DEC) Data exchange file |
| DXF | Drawing Interchange (eXchange) format,a text representation of the binary DWG format |
| DXF | Drawing Interchange Format (AutoCAD) |
| DXF | Data Exchange File |
| DXN | Fax document (Fujitsu dexNet) |
| DXR | Macromedia Director protected (not editable) movie file |
| DYN | Datafile (Lotus 1-2-3) |
| D2D | 2D/3D object file (3-D Fassade Plus) |
| D64 | Commodore 64 emulator disk image |